https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Age-Related Clinical Characteristics, Inflammatory Features, Phenotypes, and Treatment Response in Asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50571 Wed 28 Feb 2024 15:53:55 AEDT ]]> Body Composition-Specific Asthma Phenotypes: Clinical Implications https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51503 Wed 28 Feb 2024 14:50:10 AEDT ]]> Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45172 Wed 26 Oct 2022 14:18:41 AEDT ]]> Treatable Traits in Elderly Asthmatics from the Australasian Severe Asthma Network: A Prospective Cohort Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49079 Wed 03 May 2023 16:14:55 AEST ]]> A two-dimensional electron gas based on a 5s oxide with high room-temperature mobility and strain sensitivity https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48665 3 upon extrinsic La or Sb doping, which has excited significant research attention. In this work, we report the realization of a two-dimensional electron gas (2DEG) on the surface of transparent BaSnO3 via oxygen vacancy creation, which exhibits a high carrier density of ~7.72 × 1014 cm−2 and a high room-temperature mobility of ~18 cm2·V−1·s−1. Such a 2DEG is rather sensitive to strain and a less than 0.1% in-plane biaxial compressive strain leads to a giant resistance enhancement of ~350% (more than 540 kΩ/□) at room temperature. Thus, this work creates a new path to exploring the physics of low-dimensional oxide electronics and devices applicable at room temperature.]]> Tue 28 Mar 2023 10:08:04 AEDT ]]> Is the consumption of fast foods associated with asthma or other allergic diseases? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44917 P <0.001). In conclusion, the consumption of fast foods, particularly hamburgers, correlates to asthma in a dose-response pattern, which needs to be further validated in longitudinal and interventional studies.]]> Tue 25 Oct 2022 09:17:17 AEDT ]]> Heterogeneity of paucigranulocytic asthma: a prospective cohort study with hierarchical cluster analysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46337 P = .01), emergency visit (RR = 8.61, P = .03), and hospitalization (RR = 12.94, P < .01). Results of the cluster analysis were successfully validated in an independent PGA population classified using decision tree analysis. Although PGA can transform into or develop from other phenotypes, 70% were stable over time. Conclusions: Among 3 identified PGA clusters, cluster 3 had a higher risk of severe exacerbation. PGA heterogeneity indicates the requirement of novel targeted interventions.]]> Tue 15 Nov 2022 15:03:45 AEDT ]]> Reduced Skeletal Muscle Mass Is Associated with an Increased Risk of Asthma Control and Exacerbation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52770 Tue 14 Nov 2023 15:04:05 AEDT ]]> Chronic cough in asthma is associated with increased airway inflammation, more comorbidities, and worse clinical outcomes https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51598 Tue 12 Sep 2023 12:25:08 AEST ]]> Clinical and inflammatory features of exacerbation-prone asthma: a cross-sectional study using multidimensional assessment https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38811 Tue 08 Feb 2022 14:30:33 AEDT ]]> Reduced bronchodilator reversibility correlates with non-type 2 high asthma and future exacerbations: A prospective cohort study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51880 Thu 21 Sep 2023 10:25:03 AEST ]]> Clinical Subtypes of Neutrophilic Asthma: A Cluster Analysis From Australasian Severe Asthma Network https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54912 Thu 21 Mar 2024 12:03:37 AEDT ]]> Obesity-Associated Metabolic Signatures Correlate to Clinical and Inflammatory Profiles of Asthma: A Pilot Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43316 Thu 15 Sep 2022 14:15:31 AEST ]]> Total IgE Variability Is Associated with Future Asthma Exacerbations: A 1-Year Prospective Cohort Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49346 Thu 11 May 2023 16:31:08 AEST ]]> Dyslipidemia Is Associated With Worse Asthma Clinical Outcomes: A Prospective Cohort Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50719 Thu 03 Aug 2023 09:12:38 AEST ]]> Visceral obesity is associated with clinical and inflammatory features of asthma: a prospective cohort study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46500 low) and high VFA (VFAhigh) groups. Relationships between VFA and clinical and inflammatory features of asthma were analyzed by using correlation analysis. Univariate and multivariable negative binomial regression analyses were performed to investigate the association of VFA with exacerbations within a 12-month follow-up period. Results: The patients in the VFAhigh group were older and had a longer asthma duration. Interleukin (IL) 6 and IL-8 in sputum were higher, whereas fractional exhaled nitric oxide (FeNO) and blood eosinophils were lower in the VFAhigh group. Gender-differentiated correlations of VFA with clinical and inflammatory variables were observed in age, FeNO, immunoglobulin E, blood total white cells and neutrophils, and sputum IL-1β and IL-8. Furthermore, compared with the VFAlow group, the VFAhigh group was at significantly increased risk of moderate-to-severe exacerbations (adjusted incidence rate ratio [IRR] 1.55 [95% confidence interval {CI}, 1.06‐2.28; p = 0.025), severe exacerbations (adjusted IRR 2.25 [95% CI, 1.26‐4.04]; p = 0.007), and emergency visits (adjusted IRR 5.33 [95% CI, 1.78‐17.16]; p = 0.003). Conclusion: The level of VFA was associated with specific clinical and inflammatory characteristics of asthma. Furthermore, VFA, as an independent risk factor, was associated with an increased risk of exacerbations. It indicated that VFA would provide more potential clinical implications for asthma management.]]> Thu 01 Dec 2022 15:34:59 AEDT ]]> Cloud-based information infrastructure for next-generation power grid: conception, architecture, and applications https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29658 Sat 24 Mar 2018 07:41:55 AEDT ]]> Rational and self-adaptive evolutionary extreme learning machine for electricity price forecast https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29756 Sat 24 Mar 2018 07:32:17 AEDT ]]> Enabling the big data analysis in the smart grid https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23113 Sat 24 Mar 2018 07:15:31 AEDT ]]> Interaction effect of chronic cough and ageing on increased risk of exacerbation in patients with asthma: a prospective cohort study in a real-world setting https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54966 Mon 25 Mar 2024 12:11:04 AEDT ]]> Systemic inflammation mediates the detrimental effects of obesity on asthma control https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47551 Mon 23 Jan 2023 12:29:49 AEDT ]]> Antiferromagnetism in Ni-Based Superconductors https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46764 Mon 06 May 2024 15:37:59 AEST ]]> Depressive symptom‐associated IL ‐1β and TNF ‐α release correlates with impaired bronchodilator response and neutrophilic airway inflammation in asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37034 Fri 14 Aug 2020 13:03:43 AEST ]]> Sputum Metabolomic Profiling Reveals Metabolic Pathways and Signatures Associated With Inflammatory Phenotypes in Patients With Asthma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47306 Fri 13 Jan 2023 10:52:32 AEDT ]]> Clinical Phenotypes of Patients Hospitalized for an Asthma Exacerbation: Prognostic Implications https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46081 adj], 18.10 and 19.17, respectively) and mechanical ventilation (RRadj , 2.56 and 5.71, respectively) than did cluster 1. Individuals in cluster 3 had an extended length of hospital stay (11 days), increased hospitalization direct costs (13,481.57 Chinese Yuan), and a higher risk of ICU admission (RRadj , 2.14) than individuals in clusters 1 and 2. The decision tree assigned 90.8% of the participants correctly. Conclusions: We identified 3 phenotypes with differential clinical and inflammatory characteristics associated with in-hospital adverse outcomes. These new phenotypes might have important and clinically relevant implications for the management of patients hospitalized for AEs.]]> Fri 11 Nov 2022 15:15:03 AEDT ]]>